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Don't let stress get you down! This three-extract blend offers optimum support by providing some of the highest levels of key compounds found in Holy Basil Trinity Blend™ that help you adapt to stress with ease.†
Better product, better price!
* Contains higher levels of key active compounds than other leading competitive products
* The first of its kind to combine three unique extracts of Holy Basil
* Less expensive than the leading brand - your customers benefit and you save!
Elevates the mood and spirit†
* A safe, natural solution
Creates a positive, natural response to stress†
* Helps the body cope with everyday stress†
Additional Features
* All three Holy Basil extracts are grown without chemical fertilizers or pesticides
† This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
© Copyright 2008 - Enzymatic Therapy, Inc.
| Nutritional Information |
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| Serving Size: 2 Softgels | Amount/Serving | %DV |
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| Calories | 10 | | |
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| Calories from fat | 5 | | |
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| Total Fat | 0.5 | g | <1% |
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| Trinity Blend | 675 | mg | * |
 | Holy Basil (Ocimum sanctum) Leaf Extract standardized to contain a minimum of 2.5% triterpenoic acids including ursolic and oleanolic acids (550 mg)
Holy Basil (Ocimum sanctum) Leaf Supercritical Extract standardized to contain a minimum of 11% eugenol and 4% caryophyllene (100 mg)
Holy Basil (Ocimum sanctum) Leaf Steam-Distilled Extract standardized to contain a minimum of 40% eugenol and 15% caryophyllene (25 mg) |
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| Percent daily values (DV) | | | |
| are based on a 2,000 calorie diet |
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| *Daily Value (DV) not established. |
Other Ingredients
extra virgin olive oil, gelatin, vegetable glycerin, soy lecithin, caramel color, beeswax, and d-alpha tocopherol (antioxidant).
Contains No
sugar, salt, yeast, wheat, gluten, corn, dairy products, artificial flavoring or preservatives. All colors used are from natural sources.
Notes
If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.ETI is an FDA-registered Drug Establishment and an AFSI-certified producer of particular organic product(s).
Technical Data
Introduction:
The Ocimum sactum plant, a member of the mint (Labiatae) family, is native to tropical Asia. It has been cultivated in India for more than 3,000 years and has since been dispersed throughout most tropical parts of the world. 5,6
Also known as “Tulsi” or “The Incomparable One”, holy basil is one of the most sacred plants in India. In Hindu mythology, Tulsi symbolizes the goddess Lakshmi, the wife of Vishnu, who is one of the religion's most important deities. The herb has been celebrated for centuries and is still highly prized today because of its association with positive mood and increased awareness.† 6
In addition to its religious significance, holy basil has great health implications. It has been used in several ancient systems of medicine including Ayurveda, Greek, Roman, and Siddha for thousands of years. Central to its traditional uses, holy basil is said to enhance the mind, body, and spirit.† 5,6
How Does It Work?:
Holy basil leaves are a natural source of many important antioxidant compounds that provide a wide variety of health benefits. Most notably, eugenol, caryophyllene, and triterpenoic acids, such as ursolic and oleanolic acid. 5,6
Eugenol and caryophyllene are aromatic compounds, so named because of their pleasing fragrance or “aroma”. These compounds, which are present in many plants, are frequently utilized in essential oils because their fragrant scent is believed to elevate both mood and spirit.† In fact, holy basil, which possesses adaptogenic properties, has long been associated with improved mental clarity and mood.† Adaptogenic herbs are not mood altering, but rather, they help the body maintain healthy functioning during times of stress. 5,7
Traditional Indian medicine has frequently utilized holy basil for just such an effect, and now modern science is also examining this relationship. In a scientific study, an herbal preparation, which combines holy basil along with three other Ayurvedic herbs, was shown to improve the body's ability to adapt to stress.† The combination exhibited both preventative and restorative effects to stressful stimuli.† 8,9
When isolated and examined individually, holy basil was shown to significantly contribute to these effects. Several studies have shown that certain alcohol extractions of holy basil support a healthy response to stress.† Administration of the alcohol extract significantly reduced the corticosterone level, indicating the supportive potential of the plant.† 10-12
In addition, the key component eugenol, which must be obtained through other extraction methods, has been shown to possess similar effects on external stressors, though it is theorized that these components work in unique ways.† 13
Therefore, it is theorized that a combination of standardized holy basil extracts will provide the greatest benefits.
The Trinity Blend™ and Extraction Methods
Botanical extractions allow for the separation, isolation, and concentration of key active components naturally found in the herb. Extractions are also useful for producing a consistent product; one that will deliver the same amount of support with each dose. While there are many methods for extracting botanical compounds, each will affect the herb and the isolate in different ways. Certain extraction methods will isolate lipophilic (“fat-loving” or insoluble in water) components, whereas others will extract hydrophilic (“water-loving” or water soluble) components. 14,15
When both types of components are required for support, a combination of extraction methods will be required.
With this in mind, Enzymatic Therapy's Holy Basil Trinity Blend™ was designed to provide the most complete spectrum of the beneficial compounds naturally found in the leaves of Ocimum sanctum. The blend includes an alcohol extract, a supercritical extract, and a steam distilled extract of holy basil, each of which are standardized for key beneficial components. By utilizing three different extraction methods, Holy Basil Trinity Blend™ provides significantly higher levels than those found in other dietary supplements. 1-3
Alcohol extraction is one of the most commonly utilized extraction methods. The plant constituents are fully dissolved, then purified through a distillation process. Next, an alcohol is applied to extract the key components from the other alcohol-insoluble plant constituents. A secondary distillation process removes the alcohol, leaving only the pure, concentrated key components. 14-17
In addition, the Trinity Blend™ also contains a supercritical extract of the holy basil leaf. Supercritical extraction, which has become increasingly popular, uses carbon dioxide (CO2) under extremely high pressure to isolate key components. The process involves low temperatures, ensuring the ingredients are not affected by high heat that could alter or weaken the beneficial compounds. Once the extraction is completed, the carbon dioxide is re-released into the atmosphere. 18,19
Finally, during steam distillation, the plant material is permeated with steam. As the plant tissues break down, the essential oils, key compounds, and water vapor are released, then collected and cooled. The volatile essential oil condenses and separates and the key, hydrophilic components can be easily isolated. 14,20
Each of these methods yields important constituents at different potencies. The chart below provides the key components isolated in each extract of Holy Basil Trinity Blend™. 1-3
The result is a superior, high potency, broad spectrum dietary supplement.
Method Key Components (per serving)
Alcohol (solvent) Extraction 13.8 mg Triterpenoic acids
Supercritical (CO2) Extraction 11 mg Eugenol
4 mg Caryophylene
Steam (H20) Distillation 10 mg Eugenol
3.8 mg Caryophylene
CONCLUSION:
By combining three unique extractions of Ocimum sanctum, Enzymatic Therapy's Holy Basil Trinity Blend™ provides a potent, full spectrum supplement which supports a better mood, improved mental clarity, and enhances the body's ability to adapt to stress.† The Trinity Blend™ supplies the highest level of active components on the market. 1-3
Recommendations:
Two softgel capsules daily.
Precautions:
If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.
How Is It Supplied?:
Product No. 05286
60 softgel capsules
Storage Recommendations:
Store at controlled room temperature, 59° to 86°F (15° – 30°C).
References:
1. Ocimum sanctum Ext. (2.5%) (RM50.620) Analytical Specification. Natural Remedies Pvt. Ltd. Received August 15, 2005.
2. Ocimum sanctum SCF Ext. (RM50.630) Analytical Specification. Natural Remedies Pvt. Ltd. Received August 15, 2005.
3. Basil Oil (RM50.640) Typical Certificate of Analysis. Natural Remedies Pvt. Ltd. Received August 16, 2005.
4. Natural Remedies communication. Received September 14, 2005.
5. Gupta SK, Prakash J, Srivastava S. Validation of traditional claim of Tulsi, Ocimum sanctum Linn. as a medicinal plant. Indian J Exp Biol. 2002 Jul;40(7):765-73.
6. Uma Devi P. Radioprotective, anticarcinogenic and antioxidant properties of the Indian holy basil, Ocimum sanctum (Tulasi). Indian J Exp Biol. 2001 Mar;39(3):185-90.
7. Bhargava KP, Singh N. Anti-stress activity of Ocimum sanctum Linn. Indian J Med Res. 1981 March;73:443-451.
8. Bhattacharya A, Muruganandam AV, Kumar V, Bhattacharya SK. Effect of poly herbal formulation, EuMil, on neurochemical perturbations induced by chronic stress. Indian J Exp Biol. 2002 Oct;40(10):1161-3.
9. Muruganandam AV, Kumar V, Bhattacharya SK. Effect of poly herbal formulation, EuMil, on chronic stress-induced homeostatic perturbations in rats. Indian J Exp Biol. 2002 Oct;40(10):1151-60.
10. Sembulingam K, Sembulingam P, Namasivayam A. Effect of Ocimum sanctum Linn on the changes in central cholinergic system induced by acute noise stress. J Ethnopharmacol. 2005 Jan 15;96(3):477-82.
11. Sembulingam K, Sembulingam P, Namasivayam A. Effect of Ocimum sanctum Linn on noise induced changes in plasma corticosterone level. Indian J Physiol Pharmacol. 1997 Oct;41(4):429-30.
12. Archana R, Namasivayam A. Effect of Ocimum sanctum on noise induced changes in neutrophil functions. J Ethnopharmacol. 2000 Nov;73(1-2):81-5.
13. Sen P, Maiti PC, Puri S, Ray A, Audulov NA, Valdman AV. Mechanism of anti-stress activity of Ocimum sanctum Linn, eugenol and Tinospora malabarica in experimental animals. Indian J Exp Biol. 1992 Jul;30(7):592-6.
14. Kaufman PB, Cseke LJ, Warber S, Duke JA, Brielmann HL. Bioseparation of Compounds. In: Kane H, ed. Natural Products from Plants. Boca Raton, FL: CRC Press; 1999:212-225.
15. Cannell RJP, ed. Approaching an Isolation. In: Walker JM, ed. Methods in Biotechnology: Natural Products Isolation. Totowa, NJ: Humana Press Inc; 1998:40-48.
16. Cannell RJP, ed. Product Capture: Solvent Extraction. In: Walker JM, ed. Methods in Biotechnology: Natural Products Isolation. Totowa, NJ: Humana Press Inc; 1998:59-68.
17. “Solvent Extraction” International Union of Pure and Applied Chemistry (IUPAC) web site. Available at: http://www.iupac.org/goldbook/S05752.pdf. Accessed July 28, 2005
18. Cannell RJP, ed. Supercritical Fluid Methods. In: Walker JM, ed. Methods in Biotechnology: Natural Products Isolation. Totowa, NJ: Humana Press Inc; 1998:91-109.
19. “Supercritical Fluid” Wikipedia web site. Available at: http://en.wikipedia.org/wiki/Supercritical_fluid. Accessed August 12, 2005.
20. “Distillation” Wikipedia web site. Available at: http://en.wikipedia.org/wiki/Distillation. Accessed August 12, 2005.
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